Clinical Research

This Surgery is research active.

Conducting high-quality clinical research helps us to keep improving NHS care by finding out which treatments work best.

In this practice, you might be asked to take part in a clinical research study. Alternatively, ask our staff about clinical studies suitable for you.
Taking part in a clinical research study is voluntary and can be a rewarding experience.

To find local clinical research studies, go to:

To find out more about clinical research in the East Midlands visit:

To read about other patients who have benefited from taking part in clinical research visit:

We are affiliated as a research and surveillance centre for the Royal College of General Practitioners.

National Institute for Health Research

In 2006, the Department of Health set up The National Institute for Health Research (NIHR) to improve the health and wealth of the nation through Research. The NIHR Clinical Research Network (CRN) was introduced to provide the infrastructure to the NHS to allow high quality research to be set up and delivered efficiently and effectively.

Mulberry House and St Denys Surgeries are part of a network of local practices participating in research activities under the banner of CRN Wessex. To find out more about the work of the NIHR Clinical Research Network go to

What is Primary Care Research?

The CRN Primary Care speciality works in collaboration with researchers and primary care practitioners such as GPs’, practice nurses, pharmacists and dentists to promote the successful delivery of research studies in the NHS. A wide range of research studies are supported which look at:

  • Promoting a healthier lifestyle
  • Disease diagnosis and prevention
  • Management of long-term illnesses such as diabetes or hypertension
  • Prevention of future ill-health
  • Treating common conditions such as tonsillitis or influenza

What are the Benefits of GP practices taking part in research?

  • It offers patients access to new treatments
  • It brings new dimension to practice and added skills to those involved
  • It provides national gold standard training for research
  • It offers mentorship and support to those involved in research within practice

How can you help and take part?

There are various ways a patient can become involved in studies at The Surgery @ Aylestone.

  • A doctor or nurse may talk to you about a particular study and ask whether you would be interested in participating
  • You may be sent information through the post if we feel you may be a suitable participant
  • You may read information about a current study in the patient waiting room or on the surgery website and wish to take part by contacting your GP or the Research Nurse

All clinical research carried out at our surgeries is thoroughly checked and approved by ethical committees thus ensuring it is appropriate and safe to perform. Your participation is entirely voluntary and can be withdrawn by yourself at any time without any explanation required.

You are under no obligation to participate in any research project

Your care and your relationship with your doctor will not be affected in any way if you decided not to take part in a research study

You will always receive clear information about what taking part in a research study would involve. You will have the opportunity to ask questions and obtain further details about a study. 

If you do agree to take part in a study, you will be asked to sign a consent form. This will clearly state which parts of your notes (if any) may be looked at for the purposes of the research study. Nobody from outside this practice will be given your contact details or have access to your medical records without your prior consent.

Current Research Studies

Platform Randomised trial of INterventions against COVID-19 In older peopLE – The PRINCIPLE Trial

We are very fortunate to have been involved in research with the RCGP for many years. One of their current research projects is self swabbing for COVID-19.

If you have symptoms confirmed by the COVID-19 checker (link below) for LESS THAN 7 days please contact the Surgery URGENTLY to arrange collection of a self swab kit. We will get the results very quickly which will allow us to guide you on self isolation and contact tracing. This will help to reduce the spread of COVID-19.

A clinical trial exploring treatment for the COVID-19 virus is also taking place. If you experience a new or worsening continuous cough and/or a high temperature and have had it for less than 14 days and are not starting to feel better OR you have had a positive test for SARS-Co-V2 infection which was taken fewer than 15 days ago, AND are unwell with symptoms of COVID-19, please click here to find out more.

Online COVID-19 Symptom Checker –

Virus Watch

We urgently need to understand more about COVID-19. The more we understand the virus the better equipped we will be to stop its spread and save lives. Current research does a very good job of reporting infection rates and identifying outbreaks. Virus Watch aims to identify how the virus spreads, and, how to stop it and prevent a second wave. To achieve this we need help from people in every community in England and Wales – from you and your family. Join thousands of households already taking part in our Virus Watch study and together we can help beat the virus.

Chosen participants will receive antibody tests to see if they have had COVID-19 and might now have resistance against the virus. As we gather the results from our study you’ll be able to see them on our website. In this way, your family will have the very latest COVID-19 information.

This study is being run by University College London in conjunction with the NHS. Enter your email below to join our mailing list and then you and your household can register for the study.

Help stop the spread.

Register here.


EXCEED (Extended Cohort for E-health, Environment and DNA) looks at the causes of long-term health conditions by collecting information about genes and lifestyle. More than 10,000 people have already taken part.

We now aim to understand why some people develop more severe COVID-19 than others, and the impact of the pandemic on long-term conditions. This will help develop new ways to prevent or treat COVID-19 and long-term conditions during and after the pandemic. Minority ethnic and migrant communities have had higher rates of COVID-19 hospital admissions. To understand why this is happening we especially encourage volunteers to join us from these communities

Click here to take part.

Active Brains

Active Brains is an interactive website for people aged 60-85 designed to help with lifestyle changes and brain training activities that can help to keep the brain and body healthy. The study you have been invited to take part in is to test if Active Brains works.

Sign up